CDB - A database for protein heterodimeric complexes

Malka Aker, Shirly Ohanona, Shira Fisher, Efrat Katsman, Shirit Dvorkin, Efrat Kopelowitz, Moshe Goldstein, Zohar Barnett-Itzhaki, Moshe Amitay

Research output: Contribution to journalArticlepeer-review


Crystallographic structures of protein complexes are essential to develop proteomic and structural biology methods, as prediction of protein-protein interaction (PPI) sites and protein-protein docking. Such structures can aid the development of protein complexation inhibitors. Complex DataBase (CDB), accessible at, is a database web application for heterodimeric protein crystallographic complexes along with the crystallographic structures of each individual unbound protein. Direct access to crystallographic structures of protein complexes, along with provided annotations, can serve as starting point for constructing new experimental protein complexes sets of any type, for protein binding studies, and the development and evaluation of PPIs prediction methods.

Original languageEnglish
Pages (from-to)361-365
Number of pages5
JournalProtein Engineering, Design and Selection
Issue number10
StatePublished - 1 Oct 2018
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Author(s) 2018. Published by Oxford University Press. All rights reserved.


  • Crystallography
  • Protein complex interactions
  • Protein dimers
  • Protein-protein interface
  • Structure


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