Cationic antimicrobial copolymer poly (methylmethacrylate-co-PHMG) decontaminates water

Oren Aviv; Stanislav Ratner; Nir Amir; Natalia Laout; Arijit Basu; Hodaya Shadmon; Nurit Beyth; Abraham J. Domb

doi:10.1002/pat.3770

Cationic antimicrobial copolymer poly (methylmethacrylate-co-PHMG) decontaminates water

Oren Aviv, Stanislav Ratner, Nir Amir, Natalia Laout, Arijit Basu, Hodaya Shadmon, Nurit Beyth, Abraham J. Domb

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Vinyl terminated poly hexamethylene guanidine hydrochloride (PHMG) and methyl methacrylate (MMA) were copolymerized and tested for surface antimicrobial activity. PHMG chains of molecular weight ~2000 were functionalized with vinyl end groups (PHMG–C = C) by reacting the PHMG amino end groups with 1,2-epoxy-9-decene, or glycidyl methacrylate. PHMG–C = C was copolymerized with MMA at 10% w/w ratio to form water insoluble poly(MMA-co-PHMG). Films of these copolymers demonstrated strong antimicrobial activity for 3 months against Escherichia coli and heterotrophic plate count bacteria. The synthesized PHMG–MMA copolymers may be used for self-sterilizing coatings and water decontamination.

Original language	English
Pages (from-to)	1334-1338
Number of pages	5
Journal	Polymers for Advanced Technologies
Volume	28
Issue number	10
DOIs	https://doi.org/10.1002/pat.3770
State	Published - Oct 2017
Externally published	Yes

Bibliographical note

Publisher Copyright:
Copyright © 2016 John Wiley & Sons, Ltd.

Keywords

antimicrobial
cationic polymer
poly(hexamethylene guanidine) hydrochloride
water decontamination

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10.1002/pat.3770

Cite this

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abstract = "Vinyl terminated poly hexamethylene guanidine hydrochloride (PHMG) and methyl methacrylate (MMA) were copolymerized and tested for surface antimicrobial activity. PHMG chains of molecular weight ~2000 were functionalized with vinyl end groups (PHMG–C = C) by reacting the PHMG amino end groups with 1,2-epoxy-9-decene, or glycidyl methacrylate. PHMG–C = C was copolymerized with MMA at 10% w/w ratio to form water insoluble poly(MMA-co-PHMG). Films of these copolymers demonstrated strong antimicrobial activity for 3 months against Escherichia coli and heterotrophic plate count bacteria. The synthesized PHMG–MMA copolymers may be used for self-sterilizing coatings and water decontamination.",

keywords = "antimicrobial, cationic polymer, poly(hexamethylene guanidine) hydrochloride, water decontamination",

author = "Oren Aviv and Stanislav Ratner and Nir Amir and Natalia Laout and Arijit Basu and Hodaya Shadmon and Nurit Beyth and Domb, {Abraham J.}",

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AU - Aviv, Oren

AU - Ratner, Stanislav

AU - Amir, Nir

AU - Laout, Natalia

AU - Basu, Arijit

AU - Shadmon, Hodaya

AU - Beyth, Nurit

AU - Domb, Abraham J.

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AB - Vinyl terminated poly hexamethylene guanidine hydrochloride (PHMG) and methyl methacrylate (MMA) were copolymerized and tested for surface antimicrobial activity. PHMG chains of molecular weight ~2000 were functionalized with vinyl end groups (PHMG–C = C) by reacting the PHMG amino end groups with 1,2-epoxy-9-decene, or glycidyl methacrylate. PHMG–C = C was copolymerized with MMA at 10% w/w ratio to form water insoluble poly(MMA-co-PHMG). Films of these copolymers demonstrated strong antimicrobial activity for 3 months against Escherichia coli and heterotrophic plate count bacteria. The synthesized PHMG–MMA copolymers may be used for self-sterilizing coatings and water decontamination.

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KW - cationic polymer

KW - poly(hexamethylene guanidine) hydrochloride

KW - water decontamination

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Cationic antimicrobial copolymer poly (methylmethacrylate-co-PHMG) decontaminates water

Abstract

Bibliographical note

Keywords

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