Cationic antimicrobial copolymer poly (methylmethacrylate-co-PHMG) decontaminates water

Oren Aviv, Stanislav Ratner, Nir Amir, Natalia Laout, Arijit Basu, Hodaya Shadmon, Nurit Beyth, Abraham J. Domb

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Vinyl terminated poly hexamethylene guanidine hydrochloride (PHMG) and methyl methacrylate (MMA) were copolymerized and tested for surface antimicrobial activity. PHMG chains of molecular weight ~2000 were functionalized with vinyl end groups (PHMG–C = C) by reacting the PHMG amino end groups with 1,2-epoxy-9-decene, or glycidyl methacrylate. PHMG–C = C was copolymerized with MMA at 10% w/w ratio to form water insoluble poly(MMA-co-PHMG). Films of these copolymers demonstrated strong antimicrobial activity for 3 months against Escherichia coli and heterotrophic plate count bacteria. The synthesized PHMG–MMA copolymers may be used for self-sterilizing coatings and water decontamination.

Original languageEnglish
Pages (from-to)1334-1338
Number of pages5
JournalPolymers for Advanced Technologies
Issue number10
StatePublished - Oct 2017
Externally publishedYes

Bibliographical note

Publisher Copyright:
Copyright © 2016 John Wiley & Sons, Ltd.


  • antimicrobial
  • cationic polymer
  • poly(hexamethylene guanidine) hydrochloride
  • water decontamination


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