Castor Oil-Based Biodegradable Polyesters

Konda Reddy Kunduru, Arijit Basu, Moran Haim Zada, Abraham J. Domb

Research output: Contribution to journalReview articlepeer-review

127 Scopus citations

Abstract

This Review compiles the synthesis, physical properties, and biomedical applications for the polyesters based on castor oil and ricinoleic acid. Castor oil has been known for its medicinal value since ancient times. It contains ∼90% ricinoleic acid, which enables direct chemical transformation into polyesters without interference of other fatty acids. The presence of ricinoleic acid (hydroxyl containing fatty acid) enables synthesis of various polyester/anhydrides. In addition, castor oil contains a cis-double bond that can be hydrogenated, oxidized, halogenated, and polymerized. Castor oil is obtained pure in large quantities from natural sources; it is safe and biocompatible.

Original languageEnglish
Pages (from-to)2572-2587
Number of pages16
JournalBiomacromolecules
Volume16
Issue number9
DOIs
StatePublished - 14 Sep 2015
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2015 American Chemical Society.

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