Case of chest-wall rigidity in a preterm infant caused by prenatal fentanyl administration

S. Eventov-Friedman, I. Rozin, E. S. Shinwell

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The inability to appropriately ventilate neonates shortly after their birth could be related in rare cases to chest-wall rigidity caused by the placental transfer of fentanyl. Although this adverse effect is recognized when fentanyl is administered to neonates after their birth, the prenatal phenomenon is less known. Treatment with either naloxone or muscle relaxants reverses the fentanyl effect and may prevent unnecessary excessive ventilatory settings.

Original languageEnglish
Pages (from-to)149-150
Number of pages2
JournalJournal of Perinatology
Volume30
Issue number2
DOIs
StatePublished - Feb 2010
Externally publishedYes

Keywords

  • Chest-wall rigidity
  • Fentanyl
  • Lung compliance
  • Placental transfer
  • Preterm infant

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