TY - CHAP
T1 - Can Oxytocin Improve Core Brain and Behavioral Features of Asd in Children
AU - Gordon, I.
PY - 2013
Y1 - 2013
N2 - Autism Spectrum Disorders (ASDs) are a group of pervasive developmental conditions characterized in part by atypical development in social-communicative functions. Novel discoveries regarding the impact of the neuropeptide oxytocin (OT) on social behavior and its association with ASD prevalence and phenotypic presentation have generated a great deal of interest into OT’s possible role in ASD etiology and excitement about its potential as a therapeutic instrument. And yet, many challenges are faced by translational research efforts for OT in ASD. In this manuscript, some of these challenges are addressed, specifically the complexities of OT’s behavioral effects, the yet unknown long-term impact of OT, the undetermined neural mechanism underlying OT’s effects, and the non-linear impacts OT has on brain and behavior. In conclusion, guidelines for future translational research efforts are suggested
AB - Autism Spectrum Disorders (ASDs) are a group of pervasive developmental conditions characterized in part by atypical development in social-communicative functions. Novel discoveries regarding the impact of the neuropeptide oxytocin (OT) on social behavior and its association with ASD prevalence and phenotypic presentation have generated a great deal of interest into OT’s possible role in ASD etiology and excitement about its potential as a therapeutic instrument. And yet, many challenges are faced by translational research efforts for OT in ASD. In this manuscript, some of these challenges are addressed, specifically the complexities of OT’s behavioral effects, the yet unknown long-term impact of OT, the undetermined neural mechanism underlying OT’s effects, and the non-linear impacts OT has on brain and behavior. In conclusion, guidelines for future translational research efforts are suggested
UR - https://link.springer.com/chapter/10.1007/978-3-319-02904-7_11
M3 - Chapter
T3 - Research and Perspectives in Neurosciences
SP - 189
EP - 199
BT - New Frontiers in Social Neuroscience
A2 - Decety, Jean
A2 - Christen, Yuves
PB - Springer
ER -