Can ground-state destabilization of an α-nucleophile induce an α-effect?

Erwin Buncel, Shmaryahu Hoz

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

The possible importance of ground-state destabilization as the origin of the enhanced reactivity of α-nucleophiles is critically examined and it is concluded that, in general, this factor will contribute only slightly, if at all, to the manifestation of α-effects.

Original languageEnglish
Pages (from-to)4777-4780
Number of pages4
JournalTetrahedron Letters
Volume24
Issue number44
DOIs
StatePublished - 1983

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