BTK inhibition modulates multiple immune cell populations involved in the pathogenesis of immune mediated nephritis

Keyphrases

• Immune Response 100%
• Immune Parameters 100%
• Nephritis 100%
• BTK Inhibition 100%
• Nephrotoxic Serum Nephritis 60%
• Early Treatment 40%
• Lupus Nephritis 40%
• Proteinuria 40%
• CD45+ 40%
• Remission Induction 40%
• B Cells 20%
• CD4+ 20%
• Cellular Processes 20%
• Interleukin-6 20%
• Early Onset 20%
• Related Conditions 20%
• Late-onset 20%
• Kidney 20%
• CD8+ T Cells 20%
• Therapeutic Potential 20%
• Therapeutic Effect 20%
• Systemic Lupus Erythematosus 20%
• Macrophages 20%
• Disease Course 20%
• End Organ 20%
• Inducible Model 20%
• Bruton Tyrosine Kinase Inhibitor 20%
• Renal Pathology 20%
• Cell Population 20%
• Myeloid Cells 20%
• Disease Conditions 20%
• Disease Onset 20%
• Organ Complications 20%
• Disease Remission 20%
• Resident Macrophages 20%
• Treatment Induction 20%
• Passive Transfer 20%
• Treatment Cessation 20%
• Inflammatory Macrophages 20%
• Chemokine (C-C motif) Ligand 2 (CCL2) 20%
• Early Remission 20%
• Serum Transfer 20%
• CD14 20%
• B220 20%
• Renal Flare 20%
• Late Flare 20%

Medicine and Dentistry

• Cell Population 100%
• Immunocompetent Cell 100%
• Nephritic Syndrome 100%
• Disease 37%
• Macrophage 37%
• Spontaneous Remission 25%
• Lupus Nephritis 25%
• Proteinuria 25%
• B Cell 12%
• Disease Course 12%
• Bruton Tyrosine Kinase Inhibitor 12%
• Myeloid Cell 12%
• Cytotoxic T-Cell 12%
• Therapy Effect 12%
• Renal Pathology 12%
• Interleukin-6 12%
• T-Helper Cell 12%
• Blood Urea Nitrogen 12%
• Systemic Lupus Erythematosus 12%