Bronchodilators. 3,4,5-trihydroxyphenylethanol amines

A. Nudelman, R. J. McCaully

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


In an attempt to further define the effect of ring substitution on the β-adrenergic activity of phenylethanol amines, a group of 3,4,5-trihydroxy-substituted N-alkylphenylethanol amines were prepared. The synthesis of these compounds and their effect on bronchodilator activity and force and rate of contraction of isolated guinea pig atria are discussed.

Original languageEnglish
Pages (from-to)333-338
Number of pages6
JournalEuropean Journal of Medicinal Chemistry
Issue number4
StatePublished - 1981
Externally publishedYes


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