Abstract
In an attempt to further define the effect of ring substitution on the β-adrenergic activity of phenylethanol amines, a group of 3,4,5-trihydroxy-substituted N-alkylphenylethanol amines were prepared. The synthesis of these compounds and their effect on bronchodilator activity and force and rate of contraction of isolated guinea pig atria are discussed.
Original language | English |
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Pages (from-to) | 333-338 |
Number of pages | 6 |
Journal | European Journal of Medicinal Chemistry |
Volume | 16 |
Issue number | 4 |
State | Published - 1981 |
Externally published | Yes |