Brain Ribosomal RNA Synthesis Inhibited by Chlorpromazine

H. Breitbart, M. Perl, A. Mayevsky, E. Y. Diamant

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Injection of chlorpromazine in Charles River rats causes a depletion in 3Huridine incorporation into the brain ribosomal RNA. This phenomenon occurs in both 18s and 28s fractions. An effect on transcription may explain the (Figure presented.) reported influences of the drug on brain metabolism.

Original languageEnglish
Pages (from-to)204-207
Number of pages4
JournalExperimental Biology and Medicine
Issue number1
StatePublished - May 1973


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