Brain Ribosomal RNA Synthesis Inhibited by Chlorpromazine

H. Breitbart; M. Perl; A. Mayevsky; E. Y. Diamant

doi:10.3181/00379727-143-37286

Brain Ribosomal RNA Synthesis Inhibited by Chlorpromazine

H. Breitbart, M. Perl, A. Mayevsky, E. Y. Diamant

Research output: Contribution to journal › Article › peer-review

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Abstract

Injection of chlorpromazine in Charles River rats causes a depletion in 3Huridine incorporation into the brain ribosomal RNA. This phenomenon occurs in both 18s and 28s fractions. An effect on transcription may explain the (Figure presented.) reported influences of the drug on brain metabolism.

Original language	English
Pages (from-to)	204-207
Number of pages	4
Journal	Experimental Biology and Medicine
Volume	143
Issue number	1
DOIs	https://doi.org/10.3181/00379727-143-37286
State	Published - May 1973

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title = "Brain Ribosomal RNA Synthesis Inhibited by Chlorpromazine",

abstract = "Injection of chlorpromazine in Charles River rats causes a depletion in 3Huridine incorporation into the brain ribosomal RNA. This phenomenon occurs in both 18s and 28s fractions. An effect on transcription may explain the (Figure presented.) reported influences of the drug on brain metabolism.",

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Brain Ribosomal RNA Synthesis Inhibited by Chlorpromazine

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