Boranophosphate isoster controls P2Y-receptor subtype selectivity and metabolic stability of dinucleoside polyphosphate analogues

Keyphrases

• Borophosphate 100%
• Dinucleoside Polyphosphates 100%
• Drug Candidates 33%
• EC50 66%
• Highly Selective 33%
• Hydrolysis 33%
• Metabolic Stability 100%
• NPP1 33%
• Nucleobases 33%
• P2 Receptors 33%
• P2Y Receptors 100%
• P2Y1 33%
• Phosphate Group 33%
• Physiological Effects 33%
• Polyps 33%
• Receptor Agonist 33%
• Receptor Subtype Selectivity 100%

Biochemistry, Genetics and Molecular Biology

• Adenosine Diphosphate 50%
• Agonist 100%
• EC50 100%
• Eicosanoid Receptor 50%
• Enzymatic Hydrolysis 50%
• Nucleobase 50%
• P2 Receptor 50%
• P2Y Receptor 100%
• Receptor Agonists 50%
• Uridine Diphosphate 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Adenosine Diphosphate 25%
• Nucleic Acid Base 25%
• Polyphosphate 100%
• Purinergic P2 Receptor 25%
• Purinergic P2Y Receptor 100%
• Receptor Agonist 25%
• Receptor Subtype 100%
• Uridine Diphosphate 25%