TY - JOUR
T1 - Bloating and Abdominal Distension
T2 - Clinical Approach and Management
AU - Mari, Amir
AU - Backer, Fadi Abu
AU - Mahamid, Mahmud
AU - Amara, Hana
AU - Carter, Dan
AU - Boltin, Doron
AU - Dickman, Ram
N1 - Publisher Copyright:
© The Author(s) 2019.
PY - 2019/5
Y1 - 2019/5
N2 - Functional abdominal bloating and distension (FABD) are common gastrointestinal complaints, encountered on a daily basis by gastroenterologists and healthcare providers. Functional abdominal bloating is a subjective sensation that is commonly associated with an objective abdominal distension. FABD may be diagnosed as a single entity (the sole or cardinal complaint) or may overlap with other functional gastrointestinal disorders such as functional constipation, irritable bowel syndrome, and functional dyspepsia. The pathophysiology of FABD is not completely understood. Proposed underlying mechanisms include visceral hypersensitivity, behavioral induced abnormal abdominal wall-phrenic reflexes, the effect of poorly absorbed fermentable carbohydrates, and microbiome alterations. Management includes behavioral therapy, dietary interventions, microbiome modulation, and medical therapy. This review presents the current knowledge on the pathophysiology, evaluation, and management of FABD.
AB - Functional abdominal bloating and distension (FABD) are common gastrointestinal complaints, encountered on a daily basis by gastroenterologists and healthcare providers. Functional abdominal bloating is a subjective sensation that is commonly associated with an objective abdominal distension. FABD may be diagnosed as a single entity (the sole or cardinal complaint) or may overlap with other functional gastrointestinal disorders such as functional constipation, irritable bowel syndrome, and functional dyspepsia. The pathophysiology of FABD is not completely understood. Proposed underlying mechanisms include visceral hypersensitivity, behavioral induced abnormal abdominal wall-phrenic reflexes, the effect of poorly absorbed fermentable carbohydrates, and microbiome alterations. Management includes behavioral therapy, dietary interventions, microbiome modulation, and medical therapy. This review presents the current knowledge on the pathophysiology, evaluation, and management of FABD.
KW - Distension
KW - Functional abdominal bloating
KW - Functional constipation
KW - Functional dyspepsia
KW - Irritable bowel syndrome
UR - http://www.scopus.com/inward/record.url?scp=85063053313&partnerID=8YFLogxK
U2 - 10.1007/s12325-019-00924-7
DO - 10.1007/s12325-019-00924-7
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C2 - 30879252
AN - SCOPUS:85063053313
SN - 0741-238X
VL - 36
SP - 1075
EP - 1084
JO - Advances in Therapy
JF - Advances in Therapy
IS - 5
ER -