Biodegradable polymers: An update

Ariella Shikanov, Neeraj Kumar, Abraham J. Domb

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations


The use of polymeric materials for the administration of pharmaceuticals, and as biomedical devices has increased dramatically. This review focuses on synthetic biodegradable polymers of current interest for medical use, based on ester and anhydride bonds. Special attention is given to factors affecting biodegradation, including: polymer structure, morphology, molecular weight, radiation, and chemical treatment, as well as the effects of drugs and plasticizers added to the polymer mass. The toxicity and biocompatibility of the polymers and their current and future applications in medicine are also briefly reviewed.

Original languageEnglish
Pages (from-to)393-399
Number of pages7
JournalIsrael Journal of Chemistry
Issue number4
StatePublished - 2005
Externally publishedYes


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