Biocompatibility Testing

Kirsten Peters, Ronald E. Unger, C. James Kirkpatrick

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

The insertion of a foreign material into the body induces a cascade of events, basically at the interface between the implanted material and the tissue, which results in the recognition of the material as foreign matter. The degree of this physiological response depends on the location of implantation and the composition and mechanical properties of the material. Thus, the body’s response to an implanted material is affected by a number of different factors. To evaluate and reduce the risk for unexpected or unwanted side effects, biocompatibility testing is used to examine new biomaterials and biomedical devices destined for implantation. The biological evaluation of the material’s safety is a complex task since it requires knowledge in the disciplines of medicine, biology, pathology, engineering and materials science.

Original languageEnglish
Title of host publicationBiomedical Materials
Subtitle of host publicationSecond Edition
PublisherSpringer International Publishing
Pages423-453
Number of pages31
ISBN (Electronic)9783030492069
ISBN (Print)9783030492052
DOIs
StatePublished - 1 Jan 2020
Externally publishedYes

Bibliographical note

Publisher Copyright:
© Springer Nature Switzerland AG 2021.

Keywords

  • Chromium
  • Lactate
  • Lymphoma
  • Nickel
  • Toxicity

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