TY - JOUR
T1 - Bifunctional chelating agents, Part 3
T2 - 4,5-bis[di(carboxymethyl)amino]-n-(aminoalkyl) valeramide, an edta with an amine functionality and amide-type linker arm
AU - Warshawsky, Abraham
AU - Altman, Janina
AU - Arad-Yellin, Rina
AU - Gottlieb, Hugo E.
AU - Deshe, Abraham
AU - Kahana, Nava
AU - Shoef, Nurit
AU - Wilchek, Meir
PY - 1989
Y1 - 1989
N2 - Synthesis of bifunctional EDTA compounds with an ε-amino functionality linked through an amidoalkyl linker group derived from the previously described 4,5-diaminovaleric acid. Protection of the vicinal diamine with Boc groups and chain extension with monobenzyloxycarbonylalkylamines. Removal of the Boc groups and alkylation with bromoacetic acid (or esters), or further removal of the Ζ groups provides the amino EDTA compounds (8).
AB - Synthesis of bifunctional EDTA compounds with an ε-amino functionality linked through an amidoalkyl linker group derived from the previously described 4,5-diaminovaleric acid. Protection of the vicinal diamine with Boc groups and chain extension with monobenzyloxycarbonylalkylamines. Removal of the Boc groups and alkylation with bromoacetic acid (or esters), or further removal of the Ζ groups provides the amino EDTA compounds (8).
UR - http://www.scopus.com/inward/record.url?scp=0004655435&partnerID=8YFLogxK
U2 - 10.1039/p19890001781
DO - 10.1039/p19890001781
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AN - SCOPUS:0004655435
SN - 1470-4358
SP - 1781
EP - 1786
JO - Journal of the Chemical Society, Perkin Transactions 1
JF - Journal of the Chemical Society, Perkin Transactions 1
IS - 10
ER -