Attention deficit disorder and hyperactivity - Changes in hypothalamic function in hyperactive children: A new model

O. Peled, R. Carraso, H. Globman, S. Yehuda

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

This presentation proposes a dynamic integrative model for understanding attention deficit disorder and hyperactivity. The proposed model - the lapses model - is based on principles found in control systems. It suggests the existence of a compensatory system employed by the organism in order to correct its internal overload and homeostatic disturbances resulting from a hypothalamic dysfunction. The restoration of internal homeostasis requires resources needed for the interaction with the environment. Allocation of such resources results in lowered control ability to the point of total loss of contact with the environment. Thus, the compensatory system influences the data-processing ability and determines the cognitive style. The limitation of resources directed to coping with the surrounding environment, already creates a disturbance at the input level. This results in continuity-loss and data-loss due to the temporary saturation and oscillations in the arousal level. When balance is regained, the arousal level comes back to the optimal range, until such time when accumulated load will again cause a disturbance. The cycle repeats itself at varying intervals. The model relates to the interaction between three behavioral levels: biochemical-hormonal, physiological and cognitive-communicative.

Original languageEnglish
Pages (from-to)267-275
Number of pages9
JournalMedical Hypotheses
Volume48
Issue number3
DOIs
StatePublished - Mar 1997

Bibliographical note

Funding Information:
I would like to thank Professor Loriann, Director of the Endocrine Department of Echilov Hospital, Tel-Aviv, Israel and Ms Oberman, Chief Laboratory Technician at Echilov Hospital, Tel-Aviv, Israel, The Neurologic Department and the Blood Bank personnel of Hillel Yaffe Hospital, Hedera, Israel. The paper was taken from the author's PhD thesis at Bar Ilan University, Israel 1993. The work described was supervised by Professor S. Yehuda and Dr H. Globman. The thesis was sponsored by The Israeli Foundation of Research and Education Grants.

Funding

I would like to thank Professor Loriann, Director of the Endocrine Department of Echilov Hospital, Tel-Aviv, Israel and Ms Oberman, Chief Laboratory Technician at Echilov Hospital, Tel-Aviv, Israel, The Neurologic Department and the Blood Bank personnel of Hillel Yaffe Hospital, Hedera, Israel. The paper was taken from the author's PhD thesis at Bar Ilan University, Israel 1993. The work described was supervised by Professor S. Yehuda and Dr H. Globman. The thesis was sponsored by The Israeli Foundation of Research and Education Grants.

FundersFunder number
Israeli Foundation of Research and Education

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