Asymmetric synthesis of functionalized piperidine derivatives: Synthesis of (S)-anatabine

Thiagarajan Balasubramanian; Alfred Hassner

doi:10.1016/s0957-4166(98)00225-0

Asymmetric synthesis of functionalized piperidine derivatives: Synthesis of (S)-anatabine

Thiagarajan Balasubramanian
, Alfred Hassner

Department of Chemistry

Bar-Ilan University

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

A short and efficient chiral synthesis of 6-aryl-5-phenylsulfonyl- l,2,5,6-tetrahydropyridines was achieved in moderate yield and with good selectivity. The absolute configurations were assigned by extending the methodology to (S)-anatabine and as well with NMR experiments.

Original language	English
Pages (from-to)	2201-2205
Number of pages	5
Journal	Tetrahedron Asymmetry
Volume	9
Issue number	13
DOIs	https://doi.org/10.1016/s0957-4166(98)00225-0
State	Published - 3 Jul 1998

Bibliographical note

Funding Information:
Support of this research by a grant from the US-Israel Binational Science Foundation is gratefully acknowledged. We thank Professor A. I. Meyers for useful suggestions and Dr. H. E. Gottlieb for valuable help with NMR spectra.

Funding

Support of this research by a grant from the US-Israel Binational Science Foundation is gratefully acknowledged. We thank Professor A. I. Meyers for useful suggestions and Dr. H. E. Gottlieb for valuable help with NMR spectra.

Funders
United States-Israel Binational Science Foundation

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abstract = "A short and efficient chiral synthesis of 6-aryl-5-phenylsulfonyl- l,2,5,6-tetrahydropyridines was achieved in moderate yield and with good selectivity. The absolute configurations were assigned by extending the methodology to (S)-anatabine and as well with NMR experiments.",

author = "Thiagarajan Balasubramanian and Alfred Hassner",

note = "Funding Information: Support of this research by a grant from the US-Israel Binational Science Foundation is gratefully acknowledged. We thank Professor A. I. Meyers for useful suggestions and Dr. H. E. Gottlieb for valuable help with NMR spectra.",

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AU - Hassner, Alfred

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AB - A short and efficient chiral synthesis of 6-aryl-5-phenylsulfonyl- l,2,5,6-tetrahydropyridines was achieved in moderate yield and with good selectivity. The absolute configurations were assigned by extending the methodology to (S)-anatabine and as well with NMR experiments.

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Asymmetric synthesis of functionalized piperidine derivatives: Synthesis of (S)-anatabine

Abstract

Bibliographical note

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