Asymmetric synthesis of 1,4-dideoxy-1,4-imino-D-ribitol via stereoselective addition of allylphenylsulfone to an aryl N-sulfinylimine

Ramaiah Kumareswaran, Alfred Hassner

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26 Scopus citations

Abstract

Asymmetric synthesis of 1,4-dideoxy-1,4-imino-D-ribitol was achieved utilizing the stereoselective addition of allylphenylsulfone to a chiral N-sulfinyl-2-furfuryl imine and ring-closing metathesis reactions as key steps.

Original languageEnglish
Pages (from-to)3409-3415
Number of pages7
JournalTetrahedron Asymmetry
Volume12
Issue number24
DOIs
StatePublished - 21 Jan 2002

Bibliographical note

Funding Information:
Support of this research by a grant from the US–Israel Binational Science Foundation and from the Marcus Center for Medicinal and Pharmaceutical Chemistry is gratefully acknowledged. We thank Dr. H. E. Gottlieb for valuable help with NMR spectra.

Funding

Support of this research by a grant from the US–Israel Binational Science Foundation and from the Marcus Center for Medicinal and Pharmaceutical Chemistry is gratefully acknowledged. We thank Dr. H. E. Gottlieb for valuable help with NMR spectra.

FundersFunder number
US-Israel Binational Science Foundation

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