Abstract
Asymmetric syntheses of piperidine alkaloids N-acetyl-(R)-coniine and (2R,6R)-trans-solenopsin were achieved utilizing stereoselective additions of allylphenylsulfone to chiral alkyl-N-sulfinylimines and ring-closing olefin metathesis.
| Original language | English |
|---|---|
| Pages (from-to) | 2269-2276 |
| Number of pages | 8 |
| Journal | Tetrahedron Asymmetry |
| Volume | 12 |
| Issue number | 16 |
| DOIs | |
| State | Published - 13 Sep 2001 |
Bibliographical note
Funding Information:Support of this research by a grant from the US–Israel Binational Science Foundation and from the Marcus Center for Medicinal and Pharmaceutical Chemistry is gratefully acknowledged. We thank Professor A. I. Meyers for providing (S)-coniine·HCl as well as HPLC analysis of 12 and 13 , and Dr. H. E. Gottlieb for valuable help with NMR spectra.
Funding
Support of this research by a grant from the US–Israel Binational Science Foundation and from the Marcus Center for Medicinal and Pharmaceutical Chemistry is gratefully acknowledged. We thank Professor A. I. Meyers for providing (S)-coniine·HCl as well as HPLC analysis of 12 and 13 , and Dr. H. E. Gottlieb for valuable help with NMR spectra.
| Funders | Funder number |
|---|---|
| United States-Israel Binational Science Foundation |