1. The acylation of 1,3,3-trisubstituted diaziridines with acyl chlorides is realized primarily at the substituted N1 atom and is accompanied by diaziridine-hydrazone rearrangement. 2. Acylation with a 0.5-mole amount of (S)-N-tosylproline chloride is an effective method for the optical activation of 1,3,3-trialkyldiaziridines and can be used to determine the absolute configurations of these compounds.
|Number of pages
|Bulletin of the Academy of Sciences of the USSR Division of Chemical Science
|Published - Aug 1988