TY - JOUR
T1 - Associations between reported post-COVID-19 symptoms and subjective well-being, Israel, July 2021 - April 2022
AU - Gorelik, Yanay
AU - Dror, Amiel
AU - Zayyad, Hiba
AU - Wertheim, Ofir
AU - Abu Jabal, Kamal
AU - Nazzal, Saleh
AU - Otiku, Paul
AU - Elsinga, Jelte
AU - Glikman, Daniel
AU - Edelstein, Michael
N1 - Publisher Copyright:
© 2023 The Author(s). Published by Cambridge University Press.
PY - 2023/1/4
Y1 - 2023/1/4
N2 - The impact of individual symptoms reported post-COVID-19 on subjective well-being (SWB) is unknown. We described associations between SWB and selected reported symptoms following SARS-CoV-2 infection. We analysed reported symptoms and subjective well being from 2295 participants (of which 576 reporting previous infection) in an ongoing longitudinal cohort study taking place in Israel. We estimated changes in SWB associated with reported selected symptoms at three follow-up time points (3-6, 6-12 and 12-18 months post infection) among participants reporting previous SARS-CoV-2 infection, adjusted for key demographic variables, using linear regression. Our results suggest that the biggest and most sustained changes in SWB stems from non-specific symptoms (fatigue -7.7 percentage points (pp), confusion/ lack of concentration -10.7 pp, and sleep disorders -11.5pp, P < 0.005), whereas the effect of system-specific symptoms, such as musculoskeletal symptoms (weakness in muscles and muscle pain) on SWB, are less profound and more transient. Taking a similar approach for other symptoms and following individuals over time to describe trends in SWB changes attributable to specific symptoms will help understand the post-acute phase of COVID-19 and how it should be defined and better managed. Post-acute COVID19 symptoms were associated with a significant decrease in subjective well being up to 18 months after initial infection.
AB - The impact of individual symptoms reported post-COVID-19 on subjective well-being (SWB) is unknown. We described associations between SWB and selected reported symptoms following SARS-CoV-2 infection. We analysed reported symptoms and subjective well being from 2295 participants (of which 576 reporting previous infection) in an ongoing longitudinal cohort study taking place in Israel. We estimated changes in SWB associated with reported selected symptoms at three follow-up time points (3-6, 6-12 and 12-18 months post infection) among participants reporting previous SARS-CoV-2 infection, adjusted for key demographic variables, using linear regression. Our results suggest that the biggest and most sustained changes in SWB stems from non-specific symptoms (fatigue -7.7 percentage points (pp), confusion/ lack of concentration -10.7 pp, and sleep disorders -11.5pp, P < 0.005), whereas the effect of system-specific symptoms, such as musculoskeletal symptoms (weakness in muscles and muscle pain) on SWB, are less profound and more transient. Taking a similar approach for other symptoms and following individuals over time to describe trends in SWB changes attributable to specific symptoms will help understand the post-acute phase of COVID-19 and how it should be defined and better managed. Post-acute COVID19 symptoms were associated with a significant decrease in subjective well being up to 18 months after initial infection.
KW - COVID-19
KW - epidemiology
KW - public health
UR - http://www.scopus.com/inward/record.url?scp=85145897922&partnerID=8YFLogxK
U2 - 10.1017/S0950268822001996
DO - 10.1017/S0950268822001996
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C2 - 36698161
AN - SCOPUS:85145897922
SN - 0950-2688
VL - 151
JO - Epidemiology and Infection
JF - Epidemiology and Infection
M1 - e16
ER -
