Assessment of oncological safety and utility of hysteroscopy in high grade endometrial cancers: Results from an Israel gynecologic oncology group study

Ahmet Namazov, Limor Helpman, Ram Eitan, Zvi Vaknin, Ofer Lavie, Amnon Amit, Tally Levy, Inbar Ben Shachar, Ilan Atlas, Ilan Bruchim, Alon Ben Arie, Ofer Gemer

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To compare survival measures of women with Stage I high-grade endometrial cancer who underwent either hysteroscopy or a non-hysteroscopic procedure as a diagnostic procedure. Study design: 298 patients with stage I high grade endometrial cancer who underwent surgery between 2002 and 2014. Patients were divided into two groups: hysteroscopy and non-hysteroscopy (curettage or office endometrial biopsy). Clinical, pathological, and survival measures were compared between the groups. High grade histology included endometroid grade −3, uterine serous papillary carcinoma, clear cell carcinoma, and carcinosarcoma. Results: There were 71 patients in the hysteroscopy group and 227 patients in the non-hysteroscopy group. The median follow-up was 52 months (range 12–120 months). There were no differences between the groups in the 5-year recurrence-free survival (73.9 % vs. 79.7 %; p = 0.65), disease-specific survival (79.3 % vs. 83.6 %; p = 0.87), and overall survival (65.7 % vs. 80.3 %; p = 0.35). Conclusion: Hysteroscopic diagnosis in women with early-stage and high-grade endometrial cancer does not adversely affect the survival outcomes.

Original languageEnglish
Pages (from-to)67-71
Number of pages5
JournalEuropean Journal of Obstetrics, Gynecology and Reproductive Biology
Volume293
DOIs
StatePublished - Feb 2024

Bibliographical note

Publisher Copyright:
© 2023 Elsevier B.V.

Keywords

  • Endometrial cancer
  • High-grade
  • Hysteroscopy
  • Survival

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