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Artificial Intelligence In Personalized Medicine: Transforming Drug Delivery Systems

  • Rajesh Kumar
  • , Priya Sharma
  • , Amit Patel
  • All India Institute of Medical Sciences, New Delhi
  • Postgraduate Institute of Medical Education and Research
  • Indian Institute of Technology Bombay

Research output: Contribution to journalArticlepeer-review

Abstract

The integration of artificial intelligence into pharmaceutical research has ushered in a transformative era for drug discovery and development. Among various deep learning architectures, Convolutional Neural Networks (CNNs) have emerged as particularly powerful tools for modeling complex biological and chemical data. This paper provides a comprehensive review of CNN-based approaches in drug discovery, examining their applications in drug-target interaction prediction, adverse drug reaction forecasting, and de novo drug design. Through a systematic analysis of recent literature and experimental studies, we demonstrate that CNN architectures achieve superior performance across multiple pharmaceutical applications, with drug-target interaction prediction accuracies reaching 93 - 95 and adverse drug reaction detection rates of 78. The review synthesizes findings from 2018-2025, highlighting how CNNs effectively extract spatial patterns from molecular representations, identify critical features from protein sequences, and integrate with complementary architectures such as graph neural networks and long short-term memory networks. We also address key challenges including data quality limitations, model interpretability concerns, and regulatory integration pathways. This paper concludes by outlining future research directions, emphasizing the potential of hybrid architectures, multi-modal learning, and explainable AI in advancing CNN-driven drug discovery toward clinical implementation.

Original languageEnglish
Pages (from-to)274-284
Number of pages11
JournalInternational Journal of Drug Delivery Technology
Volume16
Issue number9
DOIs
StatePublished - 2026
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2026, Dr. Yashwant Research Labs Pvt. Ltd. All rights reserved.

Keywords

  • adverse drug reaction prediction
  • Convolutional Neural Networks
  • deep learning
  • drug discovery
  • drug-target interaction
  • pharmaceutical AI

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