Application of ultrasound in vaccination against goldfish ulcer disease: A pilot study

Noy Navot; Michael S. Sinyakov; Ramy R. Avtalion

doi:10.1016/j.vaccine.2010.12.069

Application of ultrasound in vaccination against goldfish ulcer disease: A pilot study

Noy Navot, Michael S. Sinyakov, Ramy R. Avtalion

The Mina and Everard Goodman Faculty of Life Sciences

Bar-Ilan University

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Antigenicity and immunogenicity of Aeromonas salmonicida soluble A-layer protein (AP) and formalin-killed bacterin were assessed in goldfish (Carassius auratus L.) by applying ultrasound-immersion (USI) and injection (Inj) routes. No adjuvant was used in USI while IFA was used in Inj. The USI treated fish did not produce detectable acquired antibodies; however, this group stimulated by AP proved to be best protected against challenge infection with a homologous virulent strain of A. salmonicida. The results reveal the asset of USI technique in fish vaccination and indicate the option of designing a pure AP-based ballast-free vaccine.

Original language	English
Pages (from-to)	1382-1389
Number of pages	8
Journal	Vaccine
Volume	29
Issue number	7
DOIs	https://doi.org/10.1016/j.vaccine.2010.12.069
State	Published - 4 Feb 2011

Keywords

Aeromonas salmonicida
Fish
Ultrasound

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.vaccine.2010.12.069

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AB - Antigenicity and immunogenicity of Aeromonas salmonicida soluble A-layer protein (AP) and formalin-killed bacterin were assessed in goldfish (Carassius auratus L.) by applying ultrasound-immersion (USI) and injection (Inj) routes. No adjuvant was used in USI while IFA was used in Inj. The USI treated fish did not produce detectable acquired antibodies; however, this group stimulated by AP proved to be best protected against challenge infection with a homologous virulent strain of A. salmonicida. The results reveal the asset of USI technique in fish vaccination and indicate the option of designing a pure AP-based ballast-free vaccine.

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Application of ultrasound in vaccination against goldfish ulcer disease: A pilot study

Abstract

Keywords

UN SDGs

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