TY - JOUR
T1 - Antimicrobial properties of the polyaniline composites against pseudomonas aeruginosa and klebsiella pneumoniae
AU - Maruthapandi, Moorthy
AU - Saravanan, Arumugam
AU - Luong, John H.T.
AU - Gedanken, Aharon
N1 - Publisher Copyright:
© 2020 MDPI AG. All rights reserved.
PY - 2020/9
Y1 - 2020/9
N2 - CuO∗TiO2∗Or SiO2was decorated on polyaniline (PANI) by a sonochemical method, and their antimicrobial properties were investigated for two common Gram-negative pathogens: Pseudomonas aeruginosa (PA) and Klebsiella pneumoniae (KP). Without PANI, CuO, TiO2, or SiO2with a concentration of 220 μg/mL exhibited no antimicrobial activities. In contrast, PANI-CuO and PANI-TiO2(1 mg/mL, each) completely suppressed the PA growth after 6 h of exposure, compared to 12 h for the PANI-SiO2at the same concentration. The damage caused by PANI-SiO2to KP was less effective, compared to that of PANI-TiO2with the eradication time of 12 h versus 6 h, respectively. This bacterium was not affected by PANI-CuO. All the composites bind tightly to the negative groups of bacteria cell walls to compromise their regular activities, leading to the damage of the cell wall envelope and eventual cell lysis.
AB - CuO∗TiO2∗Or SiO2was decorated on polyaniline (PANI) by a sonochemical method, and their antimicrobial properties were investigated for two common Gram-negative pathogens: Pseudomonas aeruginosa (PA) and Klebsiella pneumoniae (KP). Without PANI, CuO, TiO2, or SiO2with a concentration of 220 μg/mL exhibited no antimicrobial activities. In contrast, PANI-CuO and PANI-TiO2(1 mg/mL, each) completely suppressed the PA growth after 6 h of exposure, compared to 12 h for the PANI-SiO2at the same concentration. The damage caused by PANI-SiO2to KP was less effective, compared to that of PANI-TiO2with the eradication time of 12 h versus 6 h, respectively. This bacterium was not affected by PANI-CuO. All the composites bind tightly to the negative groups of bacteria cell walls to compromise their regular activities, leading to the damage of the cell wall envelope and eventual cell lysis.
KW - Antimicrobials
KW - Carbon dots
KW - CuO
KW - Klebsiella pneumoniae
KW - PANI-composites
KW - Polyaniline (PANI)
KW - Pseudomonas aeruginosa
KW - SiO
KW - TiO
KW - Ultrasonication
UR - http://www.scopus.com/inward/record.url?scp=85092331953&partnerID=8YFLogxK
U2 - 10.3390/jfb11030059
DO - 10.3390/jfb11030059
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C2 - 32824954
AN - SCOPUS:85092331953
SN - 2079-4983
VL - 11
JO - Journal of Functional Biomaterials
JF - Journal of Functional Biomaterials
IS - 3
M1 - 59
ER -