Anti-angiogenic activities of hypericin in vivo: Potential for ophthalmologic applications

Keyphrases

• Ophthalmological 100%
• Hypericin 100%
• Antiangiogenic Activity 100%
• Angiogenesis 28%
• ERK2 28%
• Fibroblast Growth factor-2 (FGF-2) 28%
• Cornea 14%
• Cell Properties 14%
• Endothelial Cells 14%
• Phosphorylation 14%
• Blood Vessels 14%
• Potent Inhibitor 14%
• Hybridoma 14%
• Neovascularization 14%
• Hypoxia-inducible factor-1α (HIF-1α) 14%
• Dosing Regimen 14%
• Human Microvascular Endothelial Cells 14%
• Iris 14%
• Retinal pigment Epithelium 14%
• Ocular Administration 14%
• Inoculation 14%
• Transactivation 14%
• Rat Eye 14%
• Angiogenesis Inhibition 14%
• Angiogenesis Inhibitors 14%
• Intraperitoneal Route 14%
• Anterior Eye 14%
• Animal Treatment 14%
• Extracellular Signal-regulated MAP Kinases 14%
• Vessel Sprouting 14%
• MT1-MMP 14%
• MMP Activity 14%
• Ocular Model 14%

Neuroscience

• In Vivo 100%
• Hypericin 100%
• Angiogenesis 57%
• Basic Fibroblast Growth Factor 28%
• Mitogen Activated Protein Kinase 3 28%
• Cornea 14%
• Vascular Endothelial Growth Factor 14%
• Mitogen-Activated Protein Kinase 14%
• Epithelial Cells 14%
• Visual Pigment 14%
• Hypoxia Inducible Factor 1 14%
• Iris 14%
• Matrix Metalloproteinase 14 14%
• Transactivation 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Antiangiogenic 100%
• Hypericin 100%
• Mitogen Activated Protein Kinase 3 28%
• Fibroblast Growth Factor 2 28%
• Mitogen Activated Protein Kinase 14%
• Agents Acting on the Eye 14%
• Vasculotropin 14%
• Hypoxia Inducible Factor 1 14%
• Visual Pigment 14%
• Neovascularization (Pathology) 14%
• Matrix Metalloproteinase 14 14%