Anaphylaxis-related posttraumatic stress disorder

Y. Tal, O. Toker, AY. Hershko, G. Shany, Eyal Mizrahi, Ariel Havlin, Yaarit Ribak, S. Freedman Goldstone

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


RATIONALE: Post-traumatic stress disorder (PTSD) is a chronic and disabling entity, which negatively impacts health and quality of life. It occurs after events that are perceived as life-threatening and has a lifetime rate of 7%. Strikingly, there is very little data on anaphylaxis-related PTSD. We hypothesized that the emotional sequelae of severe anaphylaxis have been overlooked thus far and warrant investigation. METHODS: We recruited subjects with hymenoptera-venom allergy in 4 medical centers in Jerusalem, Israel. Patients were divided according to local reactions (LR) or anaphylaxis. For each subject, 3 questionnaires were used: 1) Demographic and medical data form; 2) Life Events Checklist for DSM-5 (LEC5); 3) PTSD checklist for DSM-5 (PCL5). RESULTS: A total of 89 subjects were enrolled with an average age of 38 yrs (615.1). Of these, 46 (52%) had anaphylaxis and 43 (48%) had LR. Among patients with anaphylaxis, the rate of probable PTSD was 15.2 % (N57) compared to 2.3% in the LR group (N51) (p
Original languageAmerican English
Title of host publicationJournal of Allergy and Clinical Immunology
Subtitle of host publicationPart of special issue: Programs and Abstracts of Papers to be Presented During Scientific Sessions: 2019 AAAAI Annual Meeting.
PagesAB1-AB440, 1A-4A
Number of pages1
StatePublished - 2019

Publication series

NameJournal of Allergy and Clinical Immunology
Number2 Supplement
ISSN (Print)0091-6749


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