Analytical study of the effect of recombination on evolution via DNA shuffling

Weiqun Peng, Herbert Levine, Terence Hwa, David A. Kessler

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

The recombination effects on evolution through DNA shuffling which incorporates selection, recombination and point mutations were analyzed. An extreme limit of multiparent multicrossover genetic mixing employed in DNA shuffling enables to pursue analytical results for dynamical and equilibrium features. It is observed that genetic load has scaling form which is different from that without recombination. The results show finite-effect under conditions relevant to shuffling experiments.

Original languageEnglish
Article number051911
Pages (from-to)051911-1-051911-15
JournalPhysical Review E
Volume69
Issue number5 2
StatePublished - May 2004

Funding

FundersFunder number
Directorate for Mathematical and Physical Sciences0216576, 0225630

    Fingerprint

    Dive into the research topics of 'Analytical study of the effect of recombination on evolution via DNA shuffling'. Together they form a unique fingerprint.

    Cite this