An NMR and LC-MS based mixture analysis approach for structural elucidation of antimicrobial derivatives of calophyllolide

Keyphrases

• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 100%
• Antimicrobial 100%
• Structural Elucidation 100%
• Mixture Analysis 100%
• Calophyllolide 100%
• Compound II 66%
• Methoxy 66%
• Phenyl 66%
• Reaction Products 66%
• Acetamide 66%
• Dimethyl 66%
• Chromans 66%
• Ritter-type Reaction 66%
• Compound 3 66%
• Racemic Mixture 33%
• Antimicrobial Properties 33%
• Possible Mechanisms 33%
• Structural Modification 33%
• 13C NMR Spectra 33%
• Mixture Components 33%
• 1H NMR Spectra 33%
• Spectral Data 33%
• Stereogenic Centers 33%
• Compound Formation 33%
• Nitriles 33%
• Carbon-carbon Bond Cleavage 33%
• 2D NMR Experiments 33%
• LC-MS Analysis 33%
• GHMBC 33%
• Enantiomer Composition 33%
• Complete Assignment 33%
• Chemical Structural 33%
• Structurally Related Compounds 33%

Chemistry

• NMR Spectroscopy 100%
• Structure 100%
• Calophyllolide 100%
• Liquid Chromatography Mass Spectrometry 100%
• Acetamide 66%
• Ritter Amidation 66%
• Enantiomer 33%
• Phase Composition 33%
• High Performance Liquid Chromatography 33%
• 13C NMR Spectrum 33%
• Heteronuclear Multiple Bond Coherence 33%
• 1H NMR Spectrum 33%
• Two-Dimensional NMR 33%
• Nitrile 33%