An experimental evidence-based computational paradigm for new logic-gates in neuronal activity

R. Vardi, S. Guberman, A. Goldental, I. Kanter

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

We propose a new experimentally corroborated paradigm in which the functionality of the brain's logic-gates depends on the history of their activity, e.g. an OR-gate that turns into a XOR-gate over time. Our results are based on an experimental procedure where conditioned stimulations were enforced on circuits of neurons embedded within a large-scale network of cortical cells in vitro. The underlying biological mechanism is the unavoidable increase of neuronal response latency to ongoing stimulations, which imposes a non-uniform gradual stretching of network delays.

Original languageEnglish
Article number66001
JournalEPL
Volume103
Issue number6
DOIs
StatePublished - Sep 2013

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