Allergen-specific immunoglobulin E antibodies in tears and serum of vernal conjunctivitis patients

David Sompolinsky, Zemira Samrad, Aron Zavarob, Yomtov Barishakb

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Tears and sera of 53 patients of vernal conjunctivitis were examined for antibodies of the IgE type to a panel of 18 allergens. In 18 of the patients (34.0%) allergen-specific IgE was demonstrated in both tears and serum, in 3 (5.7%) in tears only, and in 4 (7.5%) in serum only. The antigen-specific reactions with tear fluid were found in patients with the highest total IgE levels, not only in tears but also in serum. This is evidence for a specific, local allergic reaction in these patients. Most positive reactions were to perennial allergens, particularly house dust mites, cat epithelium and Bermuda grass. This fact is in harmony with the lack of season-linked symptoms in most patients in this geographical area.

Original languageEnglish
Pages (from-to)317-321
Number of pages5
JournalInternational Archives of Allergy and Immunology
Volume75
Issue number4
DOIs
StatePublished - 1984

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