Advances in the development of a novel method to be used in proteomics using gold nanobeads

Heidelinde R.C. Dietrich, Ian T. Young, Yuval Garini

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations


The study of DNA-protein interactions is gaining increased attention due to their importance in cellular processes. Only a well-functioning interaction guaranties that such a process can take place without errors. So far, only a small percentage of these interactions have been unraveled, partially due to their complexity but also due to the fact that there are only a few techniques that permit the study of these interactions. In this report we describe the development of a research tool based on tethered bead motion and Resonance Light Scattering (RLS) from gold beads. This method permits the study of DNA-protein interactions and the screening of proteins binding to a specific DNA sequence.

Original languageEnglish
Article number60920C
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
StatePublished - 2006
Externally publishedYes
EventUltrasensitive and Single-Molecule Detection Technologies - San Jose, CA, United States
Duration: 21 Jan 200624 Jan 2006


  • Molecular interactions
  • Quantitative microscopy
  • Resonance light scattering
  • Single molecule detection


Dive into the research topics of 'Advances in the development of a novel method to be used in proteomics using gold nanobeads'. Together they form a unique fingerprint.

Cite this