Advances in the Development of a Novel Method to be used in Proteomics using Gold Nanobeads

HR Dietrich; IT Young; Y. Garini

Advances in the Development of a Novel Method to be used in Proteomics using Gold Nanobeads

HR Dietrich, IT Young, Y. Garini

Department of Physics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

The study of DNA-protein interactions is gaining increased attention due to their importance in cellular processes. Only a well-functioning interaction guaranties that such a process can take place without errors. So far, only a small percentage of these interactions have been unraveled, partially due to their complexity but also due to the fact that there are only a few techniques that permit the study of these interactions. In this report we describe the development of a research tool based on tethered bead motion and Resonance Light Scattering (RLS) from gold beads. This method permits the study of DNA-protein interactions and the screening of proteins binding to a specific DNA sequence.

Original language	American English
Title of host publication	Proceedings of the SPIE
State	Published - 2006

Bibliographical note

International Society for Optics and Photonics.;
Place of conference:San Jose, CA

Cite this

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title = "Advances in the Development of a Novel Method to be used in Proteomics using Gold Nanobeads",

abstract = "The study of DNA-protein interactions is gaining increased attention due to their importance in cellular processes. Only a well-functioning interaction guaranties that such a process can take place without errors. So far, only a small percentage of these interactions have been unraveled, partially due to their complexity but also due to the fact that there are only a few techniques that permit the study of these interactions. In this report we describe the development of a research tool based on tethered bead motion and Resonance Light Scattering (RLS) from gold beads. This method permits the study of DNA-protein interactions and the screening of proteins binding to a specific DNA sequence.",

author = "HR Dietrich and IT Young and Y. Garini",

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year = "2006",

language = "American English",

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AU - Dietrich, HR

AU - Young, IT

AU - Garini, Y.

N1 - International Society for Optics and Photonics.; Place of conference:San Jose, CA

PY - 2006

Y1 - 2006

N2 - The study of DNA-protein interactions is gaining increased attention due to their importance in cellular processes. Only a well-functioning interaction guaranties that such a process can take place without errors. So far, only a small percentage of these interactions have been unraveled, partially due to their complexity but also due to the fact that there are only a few techniques that permit the study of these interactions. In this report we describe the development of a research tool based on tethered bead motion and Resonance Light Scattering (RLS) from gold beads. This method permits the study of DNA-protein interactions and the screening of proteins binding to a specific DNA sequence.

AB - The study of DNA-protein interactions is gaining increased attention due to their importance in cellular processes. Only a well-functioning interaction guaranties that such a process can take place without errors. So far, only a small percentage of these interactions have been unraveled, partially due to their complexity but also due to the fact that there are only a few techniques that permit the study of these interactions. In this report we describe the development of a research tool based on tethered bead motion and Resonance Light Scattering (RLS) from gold beads. This method permits the study of DNA-protein interactions and the screening of proteins binding to a specific DNA sequence.

M3 - Conference contribution

BT - Proceedings of the SPIE

ER -

Advances in the Development of a Novel Method to be used in Proteomics using Gold Nanobeads

Abstract

Bibliographical note

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Cite this