Advances in the Development of a Novel Method to be used in Proteomics using Gold Nanobeads

HR Dietrich, IT Young, Y. Garini

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The study of DNA-protein interactions is gaining increased attention due to their importance in cellular processes. Only a well-functioning interaction guaranties that such a process can take place without errors. So far, only a small percentage of these interactions have been unraveled, partially due to their complexity but also due to the fact that there are only a few techniques that permit the study of these interactions. In this report we describe the development of a research tool based on tethered bead motion and Resonance Light Scattering (RLS) from gold beads. This method permits the study of DNA-protein interactions and the screening of proteins binding to a specific DNA sequence.
Original languageAmerican English
Title of host publicationProceedings of the SPIE
StatePublished - 2006

Bibliographical note

International Society for Optics and Photonics.;
Place of conference:San Jose, CA

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