Advances in superresolution optical fluctuation imaging (SOFI)

Thomas Dertinger, Alessia Pallaoro, Gary Braun, Sonny Ly, Ted A. Laurence, Shimon Weiss

Research output: Contribution to journalReview articlepeer-review

38 Scopus citations


We review the concept of superresolution optical fluctuation imaging (SOFI), discuss its attributes and trade-offs (in comparison with other superresolution methods), and present superresolved images taken on samples stained with quantum dots, organic dyes, and plasmonic metal nanoparticles. We also discuss the prospects of SOFI for live cell superresolution imaging and for imaging with other (non-fluorescent) contrasts.

Original languageEnglish
Pages (from-to)210-221
Number of pages12
JournalQuarterly Reviews of Biophysics
Issue number2
StatePublished - May 2013
Externally publishedYes


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