TY - JOUR
T1 - Adult Still's disease despite the presence of positive antinuclear antibodies
AU - Awad, Jamal
AU - Farah, Raymond
AU - Horn, Ivona
PY - 2007/3
Y1 - 2007/3
N2 - We report the case of a 60-year-old woman who had recently been examined for fever of unknown origin and who presented to our hospital with high fever and myalgia, weakness, sore throat, and rash. The patient had a markedly elevated serum ferritin concentration of 40,000 ng/mL and positive antinuclear antibodies (ANA) with a titer of 1/200. Despite the presence of positive ANA, the patient was diagnosed as having adult Still's disease (ASD). High-dose steroid therapy resulted in a remarkable clinical improvement. Such a severe case of systemic inflammatory response syndrome, masquerading as sepsis with a positive ANA test, has not been reported previously, at least not in the last 15 years.
AB - We report the case of a 60-year-old woman who had recently been examined for fever of unknown origin and who presented to our hospital with high fever and myalgia, weakness, sore throat, and rash. The patient had a markedly elevated serum ferritin concentration of 40,000 ng/mL and positive antinuclear antibodies (ANA) with a titer of 1/200. Despite the presence of positive ANA, the patient was diagnosed as having adult Still's disease (ASD). High-dose steroid therapy resulted in a remarkable clinical improvement. Such a severe case of systemic inflammatory response syndrome, masquerading as sepsis with a positive ANA test, has not been reported previously, at least not in the last 15 years.
KW - ANA
KW - Adult Still's disease
KW - FUO
KW - Ferritin
KW - Fever of unknown origin
UR - https://www.scopus.com/pages/publications/33847256352
U2 - 10.1016/j.ejim.2006.07.025
DO - 10.1016/j.ejim.2006.07.025
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AN - SCOPUS:33847256352
SN - 0953-6205
VL - 18
SP - 155
EP - 157
JO - European Journal of Internal Medicine
JF - European Journal of Internal Medicine
IS - 2
ER -