Adrenocortical carcinoma presenting as bilateral pitting leg oedema

Mohammad Ebrahim Naffaa, Anat Ilivitzki, Eyal Braun

Research output: Contribution to journalArticlepeer-review


We report a case of a 54-year-old woman presented with bilateral pitting leg oedema. Initial workup for common aetiologies was unrevealing and diuretic therapy was ineffective. A CT scan of the abdomen demonstrated left adrenal mass with direct invasion of the adrenal vein and inferior vena cava with direct extension to the right atrium. Adrenocortical carcinoma was confirmed in biopsy and the patient was operated within several days. Fifteen months postoperation, the patient is doing well with good performance status and still in oncological treatment and follow-up. When the common causes of bilateral oedema have been ruled out, no delay should be experienced seeking abdominal mass with vascular invasion potential, as early diagnosis and treatment may be lifesaving.

Original languageEnglish
Article number203794
JournalBMJ Case Reports
StatePublished - 18 Mar 2014
Externally publishedYes


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