Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy

B. RICHARDS; J. R.G. BASTABLE; L. FREEDMAN; R. W. GLASHAN; GLYNIS HARRIS; D. W.W. NEWLING; M. R.G. ROBINSON; P. H. SMITH; THE YORKSHIRE UROLOGY CANCER RESEARCH GROUP

doi:10.1111/j.1464-410x.1983.tb03328.x

Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy

B. RICHARDS
, J. R.G. BASTABLE
, L. FREEDMAN
, R. W. GLASHAN
, GLYNIS HARRIS
, D. W.W. NEWLING
, M. R.G. ROBINSON
, P. H. SMITH
, THE YORKSHIRE UROLOGY CANCER RESEARCH GROUP

York Teaching Hospital NHS Foundation Trust
Medical Research Council

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Abstract

Summary— Radical radiotherapy alone has been compared with radical radiotherapy followed by chemotherapy using doxorubicin (Adriamycin) and 5–fluorouracil in a randomised prospective study on 129 patients presenting with T3, NX, MO transitional cell carcinoma of the bladder. One hundred and ten patients were evaluable with a minimum follow‐up of 2 years. The addition of this form of chemotherapy did not appear to influence the survival rate or the proportion of patients free from tumour. It cannot be recommended for routine use in the primary treatment of infiltrating bladder cancer.

Original language	English
Pages (from-to)	386-391
Number of pages	6
Journal	BJU International
Volume	55
Issue number	4
DOIs	https://doi.org/10.1111/j.1464-410x.1983.tb03328.x
State	Published - Aug 1983
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1111/j.1464-410x.1983.tb03328.x

Cite this

RICHARDS, B., BASTABLE, J. R. G., FREEDMAN, L., GLASHAN, R. W., HARRIS, GLYNIS., NEWLING, D. W. W., ROBINSON, M. R. G., SMITH, P. H., & GROUP, THE. YORKSHIRE. UROLOGY. CANCER. RESEARCH. (1983). Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy. BJU International, 55(4), 386-391. https://doi.org/10.1111/j.1464-410x.1983.tb03328.x

@article{d6257abbf8d64f928f43f34adfff687e,

title = "Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy",

abstract = "Summary— Radical radiotherapy alone has been compared with radical radiotherapy followed by chemotherapy using doxorubicin (Adriamycin) and 5–fluorouracil in a randomised prospective study on 129 patients presenting with T3, NX, MO transitional cell carcinoma of the bladder. One hundred and ten patients were evaluable with a minimum follow‐up of 2 years. The addition of this form of chemotherapy did not appear to influence the survival rate or the proportion of patients free from tumour. It cannot be recommended for routine use in the primary treatment of infiltrating bladder cancer.",

author = "B. RICHARDS and BASTABLE, \{J. R.G.\} and L. FREEDMAN and GLASHAN, \{R. W.\} and GLYNIS HARRIS and NEWLING, \{D. W.W.\} and ROBINSON, \{M. R.G.\} and SMITH, \{P. H.\} and GROUP, \{THE YORKSHIRE UROLOGY CANCER RESEARCH\}",

year = "1983",

month = aug,

doi = "10.1111/j.1464-410x.1983.tb03328.x",

language = "אנגלית",

volume = "55",

pages = "386--391",

journal = "BJU International",

issn = "1464-4096",

publisher = "John Wiley and Sons Inc.",

number = "4",

}

RICHARDS, B, BASTABLE, JRG, FREEDMAN, L, GLASHAN, RW, HARRIS, GLYNIS, NEWLING, DWW, ROBINSON, MRG, SMITH, PH & GROUP, THEYORKSHIREUROLOGYCANCERRESEARCH 1983, 'Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy', BJU International, vol. 55, no. 4, pp. 386-391. https://doi.org/10.1111/j.1464-410x.1983.tb03328.x

TY - JOUR

T1 - Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy

AU - RICHARDS, B.

AU - BASTABLE, J. R.G.

AU - FREEDMAN, L.

AU - GLASHAN, R. W.

AU - HARRIS, GLYNIS

AU - NEWLING, D. W.W.

AU - ROBINSON, M. R.G.

AU - SMITH, P. H.

AU - GROUP, THE YORKSHIRE UROLOGY CANCER RESEARCH

PY - 1983/8

Y1 - 1983/8

N2 - Summary— Radical radiotherapy alone has been compared with radical radiotherapy followed by chemotherapy using doxorubicin (Adriamycin) and 5–fluorouracil in a randomised prospective study on 129 patients presenting with T3, NX, MO transitional cell carcinoma of the bladder. One hundred and ten patients were evaluable with a minimum follow‐up of 2 years. The addition of this form of chemotherapy did not appear to influence the survival rate or the proportion of patients free from tumour. It cannot be recommended for routine use in the primary treatment of infiltrating bladder cancer.

AB - Summary— Radical radiotherapy alone has been compared with radical radiotherapy followed by chemotherapy using doxorubicin (Adriamycin) and 5–fluorouracil in a randomised prospective study on 129 patients presenting with T3, NX, MO transitional cell carcinoma of the bladder. One hundred and ten patients were evaluable with a minimum follow‐up of 2 years. The addition of this form of chemotherapy did not appear to influence the survival rate or the proportion of patients free from tumour. It cannot be recommended for routine use in the primary treatment of infiltrating bladder cancer.

UR - https://www.scopus.com/pages/publications/0020540673

U2 - 10.1111/j.1464-410x.1983.tb03328.x

DO - 10.1111/j.1464-410x.1983.tb03328.x

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 6349744

AN - SCOPUS:0020540673

SN - 1464-4096

VL - 55

SP - 386

EP - 391

JO - BJU International

JF - BJU International

IS - 4

ER -

Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this