Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy

B. RICHARDS; J. R.G. BASTABLE; L. FREEDMAN; R. W. GLASHAN; GLYNIS HARRIS; D. W.W. NEWLING; M. R.G. ROBINSON; P. H. SMITH; THE YORKSHIRE UROLOGY CANCER RESEARCH GROUP

doi:10.1111/j.1464-410x.1983.tb03328.x

Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy

B. RICHARDS, J. R.G. BASTABLE, L. FREEDMAN, R. W. GLASHAN, GLYNIS HARRIS, D. W.W. NEWLING, M. R.G. ROBINSON, P. H. SMITH, THE YORKSHIRE UROLOGY CANCER RESEARCH GROUP

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Abstract

Summary— Radical radiotherapy alone has been compared with radical radiotherapy followed by chemotherapy using doxorubicin (Adriamycin) and 5–fluorouracil in a randomised prospective study on 129 patients presenting with T3, NX, MO transitional cell carcinoma of the bladder. One hundred and ten patients were evaluable with a minimum follow‐up of 2 years. The addition of this form of chemotherapy did not appear to influence the survival rate or the proportion of patients free from tumour. It cannot be recommended for routine use in the primary treatment of infiltrating bladder cancer.

Original language	English
Pages (from-to)	386-391
Number of pages	6
Journal	British Journal of Urology
Volume	55
Issue number	4
DOIs	https://doi.org/10.1111/j.1464-410x.1983.tb03328.x
State	Published - Aug 1983
Externally published	Yes

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RICHARDS, B., BASTABLE, J. R. G., FREEDMAN, L., GLASHAN, R. W., HARRIS, GLYNIS., NEWLING, D. W. W., ROBINSON, M. R. G., SMITH, P. H., & GROUP, THE. YORKSHIRE. UROLOGY. CANCER. RESEARCH. (1983). Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy. British Journal of Urology, 55(4), 386-391. https://doi.org/10.1111/j.1464-410x.1983.tb03328.x

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title = "Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy",

abstract = "Summary— Radical radiotherapy alone has been compared with radical radiotherapy followed by chemotherapy using doxorubicin (Adriamycin) and 5–fluorouracil in a randomised prospective study on 129 patients presenting with T3, NX, MO transitional cell carcinoma of the bladder. One hundred and ten patients were evaluable with a minimum follow‐up of 2 years. The addition of this form of chemotherapy did not appear to influence the survival rate or the proportion of patients free from tumour. It cannot be recommended for routine use in the primary treatment of infiltrating bladder cancer.",

author = "B. RICHARDS and BASTABLE, \{J. R.G.\} and L. FREEDMAN and GLASHAN, \{R. W.\} and GLYNIS HARRIS and NEWLING, \{D. W.W.\} and ROBINSON, \{M. R.G.\} and SMITH, \{P. H.\} and GROUP, \{THE YORKSHIRE UROLOGY CANCER RESEARCH\}",

year = "1983",

month = aug,

doi = "10.1111/j.1464-410x.1983.tb03328.x",

language = "אנגלית",

volume = "55",

pages = "386--391",

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RICHARDS, B, BASTABLE, JRG, FREEDMAN, L, GLASHAN, RW, HARRIS, GLYNIS, NEWLING, DWW, ROBINSON, MRG, SMITH, PH & GROUP, THEYORKSHIREUROLOGYCANCERRESEARCH 1983, 'Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy', British Journal of Urology, vol. 55, no. 4, pp. 386-391. https://doi.org/10.1111/j.1464-410x.1983.tb03328.x

TY - JOUR

T1 - Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy

AU - RICHARDS, B.

AU - BASTABLE, J. R.G.

AU - FREEDMAN, L.

AU - GLASHAN, R. W.

AU - HARRIS, GLYNIS

AU - NEWLING, D. W.W.

AU - ROBINSON, M. R.G.

AU - SMITH, P. H.

AU - GROUP, THE YORKSHIRE UROLOGY CANCER RESEARCH

PY - 1983/8

Y1 - 1983/8

N2 - Summary— Radical radiotherapy alone has been compared with radical radiotherapy followed by chemotherapy using doxorubicin (Adriamycin) and 5–fluorouracil in a randomised prospective study on 129 patients presenting with T3, NX, MO transitional cell carcinoma of the bladder. One hundred and ten patients were evaluable with a minimum follow‐up of 2 years. The addition of this form of chemotherapy did not appear to influence the survival rate or the proportion of patients free from tumour. It cannot be recommended for routine use in the primary treatment of infiltrating bladder cancer.

AB - Summary— Radical radiotherapy alone has been compared with radical radiotherapy followed by chemotherapy using doxorubicin (Adriamycin) and 5–fluorouracil in a randomised prospective study on 129 patients presenting with T3, NX, MO transitional cell carcinoma of the bladder. One hundred and ten patients were evaluable with a minimum follow‐up of 2 years. The addition of this form of chemotherapy did not appear to influence the survival rate or the proportion of patients free from tumour. It cannot be recommended for routine use in the primary treatment of infiltrating bladder cancer.

UR - https://www.scopus.com/pages/publications/0020540673

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DO - 10.1111/j.1464-410x.1983.tb03328.x

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SN - 0007-1331

VL - 55

SP - 386

EP - 391

JO - British Journal of Urology

JF - British Journal of Urology

IS - 4

ER -

Adjuvant Chemotherapy with Doxorubicin (Adriamycin) and 5–Fluorouracil in T3, NX, MO Bladder Cancer Treated with Radiotherapy

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