@article{30e33eb826264e539db71c74fcef0a9b,
title = "Adherence to continuous positive airway pressure treatment in patients with Alzheimer disease and obstructive sleep apnea",
abstract = "Objective: This analysis examined whether patients with Alzheimer disease (AD) tolerate continuous positive airway pressure (CPAP). Method: Thirty patients with AD were randomized to CPAP or sham CPAP and completed sleep, depression, and quality-of-life questionnaires. Participants could choose to continue treatment after the trial. Results: Patients wore CPAP for 4.8 hours per night. More depressive symptoms were associated with worse adherence (r s = -0.37; N = 30, p < 0.04). Patients who continued using CPAP had fewer depressive symptoms (t [19] = 2.45, p = 0.02) and better adherence (t [19] = 2.32, p = 0.03) during the trial. Conclusion: Patients with AD with obstructive sleep apnea can tolerate CPAP. Adherence and long-term use may be more difficult among those patients with more depressive symptoms.",
keywords = "Adherence, Alzheimer disease, CPAP, Sleep apnea",
author = "Liat Ayalon and Sonia Ancoli-Israel and Carl Stepnowsky and Matthew Marler and Palmer, {Barton W.} and Lianqi Liu and Loredo, {Jose S.} and Jody Corey-Bloom and Deborah Greenfield and Jana Cooke",
year = "2006",
month = feb,
doi = "10.1097/01.jgp.0000192484.12684.cd",
language = "אנגלית",
volume = "14",
pages = "176--180",
journal = "American Journal of Geriatric Psychiatry",
issn = "1064-7481",
publisher = "Elsevier Inc.",
number = "2",
}
