Adaptation of the cellscan technique for the scm test in breast cancer

H. Rahmani; M. Deutsch; I. Ron; S. Gerbat; R. Tirosh; A. Weinreb; S. Chaitchik; S. Lalchuk

Adaptation of the cellscan technique for the scm test in breast cancer

H. Rahmani, M. Deutsch, I. Ron, S. Gerbat, R. Tirosh, A. Weinreb, S. Chaitchik, S. Lalchuk

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

Abstract

The value of the SCM (Structuredness of Cytoplasmic Matrix) cancer test, a procedure based on the detection of differences in lymphocyte activation in the presence and absence of cancer, has remained controversial, with inconsistent results having been reported among investigators. The Cellscan, a high-precision static cytometer system, has been designed to perform the SCM test; the apparatus facilitates the polarisation measurements and can examine cells which have been separated by simpler procedures than were originally described. In this study, using methods and diagnostic criteria adapted for the Cellscan system in a hospital environment, the SCM test correctly classified over 90% (76/80) of patients with breast cancer and differentiated over 90% (72/73) of individuals without cancer.

Original language	English
Pages (from-to)	1753-1757
Number of pages	5
Journal	European Journal of Cancer
Volume	32
Issue number	10
State	Published - 1996
Externally published	Yes

Keywords

Cancer detection
Fluorescein fluorescence polarisation
Immune system
Lymphocytes
Scm test

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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AU - Rahmani, H.

AU - Deutsch, M.

AU - Ron, I.

AU - Gerbat, S.

AU - Tirosh, R.

AU - Weinreb, A.

AU - Chaitchik, S.

AU - Lalchuk, S.

PY - 1996

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AB - The value of the SCM (Structuredness of Cytoplasmic Matrix) cancer test, a procedure based on the detection of differences in lymphocyte activation in the presence and absence of cancer, has remained controversial, with inconsistent results having been reported among investigators. The Cellscan, a high-precision static cytometer system, has been designed to perform the SCM test; the apparatus facilitates the polarisation measurements and can examine cells which have been separated by simpler procedures than were originally described. In this study, using methods and diagnostic criteria adapted for the Cellscan system in a hospital environment, the SCM test correctly classified over 90% (76/80) of patients with breast cancer and differentiated over 90% (72/73) of individuals without cancer.

KW - Cancer detection

KW - Fluorescein fluorescence polarisation

KW - Immune system

KW - Lymphocytes

KW - Scm test

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Adaptation of the cellscan technique for the scm test in breast cancer

Abstract

Keywords

UN SDGs

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