TY - JOUR
T1 - Acute tumor lysis syndrome induced by high-dose corticosteroids in a patient with chronic lymphatic leukemia
AU - Vaisban, E.
AU - Zaina, A.
AU - Braester, A.
AU - Manaster, J.
AU - Horn, Y.
PY - 2001/5
Y1 - 2001/5
N2 - Acute tumor lysis syndrome (TLS) has been reported in hematological malignancies, such as aggressive non-Hodgkin's lymphoma, acute lymphoblastic leukemia, and rarely, in other malignancies (solid tumors) in association with the administration of cytotoxic therapy. We report a case of a patient with chronic lymphatic leukemia (CLL) who developed autoimmune hemolytic anemia treated by high dose corticosteroids and, following this treatment, developed acute tumor lysis syndrome. Only one similar case has been reported recently. Clinicians should be aware that corticosteroids alone may produce this potentially life-threatening complication.
AB - Acute tumor lysis syndrome (TLS) has been reported in hematological malignancies, such as aggressive non-Hodgkin's lymphoma, acute lymphoblastic leukemia, and rarely, in other malignancies (solid tumors) in association with the administration of cytotoxic therapy. We report a case of a patient with chronic lymphatic leukemia (CLL) who developed autoimmune hemolytic anemia treated by high dose corticosteroids and, following this treatment, developed acute tumor lysis syndrome. Only one similar case has been reported recently. Clinicians should be aware that corticosteroids alone may produce this potentially life-threatening complication.
KW - Chronic lymphatic leukemia and corticosteroids
KW - Tumor lysis syndrome (TLS)
UR - http://www.scopus.com/inward/record.url?scp=0034992667&partnerID=8YFLogxK
U2 - 10.1007/s002770000276
DO - 10.1007/s002770000276
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C2 - 11446738
AN - SCOPUS:0034992667
SN - 0939-5555
VL - 80
SP - 314
EP - 315
JO - Annals of Hematology
JF - Annals of Hematology
IS - 5
ER -