TY - GEN
T1 - Acute ST elevation myocardial infarction during intravenous immunoglobulin infusion
AU - Barsheshet, Alon
AU - Marai, Ibrahim
AU - Appel, Shmulik
AU - Zimlichman, Eyal
PY - 2007/9
Y1 - 2007/9
N2 - Intravenous immunoglobulin (IVIG) preparations are increasingly being used in the treatment of autoimmune disorders. This treatment is regarded as generally safe, and most of the adverse effects associated with IVIG administration are mild and transient. This paper reports a 72-year-old patient with known is chemic heart disease admitted for a Guillain-Barré syndrome variant, who developed acute ST elevation myocardial infarction (MI) during the first hours of IVIG infusion. The literature on acute MI during IVIG treatment is reviewed. Evaluation of each patient for cardiovascular risk prior to IVIG treatment is recommended as is the assessment of risk versus benefit. If IVIG is prescribed, we propose close monitoring and slow infusion rate.
AB - Intravenous immunoglobulin (IVIG) preparations are increasingly being used in the treatment of autoimmune disorders. This treatment is regarded as generally safe, and most of the adverse effects associated with IVIG administration are mild and transient. This paper reports a 72-year-old patient with known is chemic heart disease admitted for a Guillain-Barré syndrome variant, who developed acute ST elevation myocardial infarction (MI) during the first hours of IVIG infusion. The literature on acute MI during IVIG treatment is reviewed. Evaluation of each patient for cardiovascular risk prior to IVIG treatment is recommended as is the assessment of risk versus benefit. If IVIG is prescribed, we propose close monitoring and slow infusion rate.
KW - Autoimmunity
KW - Guillain-Barré syndrome
KW - Intravenous immunoglobulin
KW - Myocardial infarction
UR - http://www.scopus.com/inward/record.url?scp=35748967576&partnerID=8YFLogxK
U2 - 10.1196/annals.1423.033
DO - 10.1196/annals.1423.033
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C2 - 17911446
AN - SCOPUS:35748967576
SN - 1573317098
SN - 9781573317092
T3 - Annals of the New York Academy of Sciences
SP - 315
EP - 318
BT - Autoimmunity, Part B Novel Applications of Basic Research
PB - Blackwell Publishing Inc.
ER -