Active RNA polymerase II curbs chromatin movement

Hodaya Hochberg-Laufer; Yaron Shav-Tal

doi:10.1083/jcb.201903050

Active RNA polymerase II curbs chromatin movement

Hodaya Hochberg-Laufer, Yaron Shav-Tal

The Mina and Everard Goodman Faculty of Life Sciences

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Chromosomes are not very mobile during interphase. In this issue, Nagashima et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb. 201811090) propose that the overall stabilization of genome structure is achieved by loose connections between DNA regions brought about by transcriptionally active RNA polymerases.

Original language	English
Pages (from-to)	1427-1428
Number of pages	2
Journal	Journal of Cell Biology
Volume	218
Issue number	5
DOIs	https://doi.org/10.1083/jcb.201903050
State	Published - 6 May 2019

Bibliographical note

Funding Information:
Yaron Shav-Tal is supported by the Israel Science Foundation and the Germany-Israel Foundation.

Publisher Copyright:
© 2019 Hochberg-Laufer and Shav-Tal.

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10.1083/jcb.201903050

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Active RNA polymerase II curbs chromatin movement

Abstract

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