Action and Ion Mobility Spectroscopy of a Shortened Retinal Derivative

Lihi Musbat, Shirrel Assis, Jonathan M. Dilger, Tarick J. El-Baba, Daniel R. Fuller, Jeppe Langeland Knudsen, Hjalte V. Kiefer, Amiram Hirshfeld, Noga Friedman, Lars H. Andersen, Mordechai Sheves, David E. Clemmer, Yoni Toker

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The development of tandem ion mobility spectroscopy (IMS) known as IMS-IMS has led to extensive research into isomerizations of isolated molecules. Many recent works have focused on the retinal chromophore which is the optical switch used in animal vision. Here, we study a shortened derivative of the chromophore, which exhibits a rich IM spectrum allowing for a detailed analysis of its isomerization pathways, and show that the longer the chromophore is, the lower the barrier energies for isomerization are. [Figure not available: see fulltext.].

Original languageEnglish
Pages (from-to)2152-2159
Number of pages8
JournalJournal of the American Society for Mass Spectrometry
Issue number11
StatePublished - 1 Nov 2018

Bibliographical note

Publisher Copyright:
© 2018, American Society for Mass Spectrometry.


We would like to thank Evan Bieske for sharing his data on PSB2 and for stimulating conversations, and Steen Brøndsted Nielsen for his valuable input. Funding Information This study was funded by the Israeli Science Foundation and by the Israeli ministry of science technology and space.

FundersFunder number
Israeli Science Foundation
Israeli ministry of science technology and space
Ministry of science and technology, Israel


    • Action spectroscopy
    • Ion mobility spectroscopy
    • Retinal protonated Schiff base
    • Vision


    Dive into the research topics of 'Action and Ion Mobility Spectroscopy of a Shortened Retinal Derivative'. Together they form a unique fingerprint.

    Cite this