Abstract
Superresolution Optical Fluctuation Imaging (SOFI) as initially demonstrated allows for a resolution enhancement in imaging by a factor of square-root of two. Here, we demonstrate how to increase the resolution of SOFI images by re-weighting the Optical Transfer Function (OTF). Furthermore, we demonstrate how cross-cumulants can be exploited to obtain a fair approximation of the underlying Point-Spread Function. We show a two-fold increase of resolution (over the diffraction limit) of nearinfrared quantum dot labeled tubulin-network of 3T3 fibroblasts.
Original language | English |
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Pages (from-to) | 18875-18885 |
Number of pages | 11 |
Journal | Optics Express |
Volume | 18 |
Issue number | 18 |
DOIs | |
State | Published - 30 Aug 2010 |
Externally published | Yes |