Abnormal cytoplasmic extensions associated with active αIIbβ3 are probably the cause for macrothrombocytopenia in Glanzmann thrombasthenia-like syndrome

Keyphrases

• Glanzmann Thrombasthenia 100%
• Glanzmann 100%
• Macrothrombocytopenia 100%
• Amino Acids 33%
• Platelet Aggregation 33%
• Constitutive Activation 33%
• Protrusion 33%
• Autosomal Recessive 33%
• Tubulin 33%
• Surface Expression 33%
• Von Willebrand Factor 33%
• Missense mutation 33%
• Cultured Cells 33%
• Cytoskeleton Remodeling 33%
• Fibrinogen 33%
• Tail Domain 33%
• Proplatelet Formation 33%
• Rare mutation 33%
• Active Conformation 33%
• Italian Families 33%
• Bleeding Disorders 33%
• Megakaryocytes 33%
• Heterozygous State 33%
• Platelet Integrin 33%
• Platelet Size 33%
• Platelet number 33%
• ITGB3 Gene 33%
• Epidermal Growth Factor-like Domain 33%
• Proplatelet 33%
• Japanese Family 33%
• Autosomal Recessive Inheritance 33%
• ITGB2 Gene 33%

Biochemistry, Genetics and Molecular Biology

• Wild Type 100%
• Thrombocytopenia 100%
• Glanzmann's Thrombasthenia 100%
• Surface Property 25%
• Conformation 25%
• Amino Acids 25%
• Tubulin 25%
• Fibrinogen 25%
• Platelet 25%
• Cell Culture 25%
• Missense Mutation 25%
• Thrombocyte Aggregation 25%
• Autosomal Dominant Inheritance 25%
• Platelet Count 25%
• Autosomal Recessive Inheritance 25%
• ITGA2B 25%
• Growth Factor-Like Domain 25%
• Integrin 25%
• Von Willebrand Factor 25%
• Megakaryocyte 25%
• Epidermal Growth Factor 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Syndrome 100%
• Glanzmann Disease 100%
• Thrombocytopenia 100%
• Integrin 33%
• Amino Acid 33%
• Absence 33%
• Tubulin 33%
• Bleeding Disorder 33%
• Fibrinogen 33%
• Epidermal Growth Factor 33%
• Von Willebrand Factor 33%