A novel method for sensing metastatic cells in the CSF of pediatric population with medulloblastoma by frequency domain FLIM system

Gilad Yahav, Dror Fixler, Sivan Gershanov, Nitza Goldenberg-Cohen

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Brain tumors are the second leading cause of cancer-related deaths in children, after leukemia. Patients with cancer in the central nervous system have a very low recovery rate. Today known imaging and cytology techniques are not always sensitive enough for an early detection of both tumor and its metastatic spread, moreover the detection is generally limited, reviewer dependent and takes a relatively long time. Medulloblastoma (MB) is the most common malignant brain tumor in children. The aim of our talk is to present the frequency domain fluorescence lifetime imaging microscopy system as a possible method for an early detection of MB and its metastatic spread in the cerebrospinal fluids within the pediatric population.

Original languageEnglish
Title of host publicationNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII
EditorsAlexander N. Cartwright, Dan V. Nicolau
PublisherSPIE
ISBN (Electronic)9781628419559
DOIs
StatePublished - 2016
EventNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII - San Francisco, United States
Duration: 15 Feb 201617 Feb 2016

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9721
ISSN (Print)1605-7422

Conference

ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII
Country/TerritoryUnited States
CitySan Francisco
Period15/02/1617/02/16

Bibliographical note

Publisher Copyright:
© 2016 SPIE.

Keywords

  • Brain tumors
  • Central nervous system (CNS)
  • Fluorescence lifetime (FLT)
  • Fluorescence lifetime imaging microscopy (FLIM)
  • Medulloblastoma (MB)

Fingerprint

Dive into the research topics of 'A novel method for sensing metastatic cells in the CSF of pediatric population with medulloblastoma by frequency domain FLIM system'. Together they form a unique fingerprint.

Cite this