@inproceedings{41f1d643ec374b7abe942ccb37a9c6b6,
title = "A new optical method for characterizing single molecule interactions based on dark field microscopy",
abstract = "Single-molecule techniques continue to gain in popularity in research disciplines such as the study of intermolecular interactions. These techniques provide information that otherwise would be lost by using bulk measurements that deal with a large number of molecules. We describe in this report the motion of tethered DNA molecules that have been tagged with gold nanobeads and observed under dark field microscopy to study single molecular interactions (SMI). We further report on the derivation and use of several physical parameters and how these parameters change under differing experimental conditions.",
keywords = "Dark field microscopy, Gold nanobeads, Molecular interactions, Single molecule detection, Tethered-particle motion",
author = "Dietrich, {Heidelinde R.C.} and Vermolen, {Bart J.} and Bernd Rieger and Young, {Ian T.} and Yuval Garini",
year = "2007",
doi = "10.1117/12.699040",
language = "אנגלית",
isbn = "0819465577",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Ultrasensitive and Single-Molecule Detection Technologies II",
note = "Ultrasensitive and Single-Molecule Detection Technologies II ; Conference date: 20-01-2007 Through 23-01-2007",
}