A Contact-Free Optical Device for the Detection of Pulmonary Congestion—A Pilot Study

Ilan Merdler, Aviram Hochstadt, Eihab Ghantous, Lior Lupu, Ariel Borohovitz, David Zahler, Philippe Taieb, Ben Sadeh, Zeev Zalevsky, Javier Garcia-Monreal, Michael Shergei, Maxim Shatsky, Yoav Beck, Sagi Polani, Yaron Arbel

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The cost of heart failure hospitalizations in the US alone is over USD 10 billion per year. Over 4 million Americans are hospitalized every year due to heart failure (HF), with a median length of stay of 4 days and an in-hospital mortality rate that exceeds 5%. Hospitalizations of patients with HF can be prevented by early detection of lung congestion. Our study assessed a new contact-free optical medical device used for the early detection of lung congestion. Methods: The Gili system is an FDA-cleared device used for measuring chest motion vibration data. Lung congestion in the study was assessed clinically and verified via two cardiologists. An algorithm was developed using machine learning techniques, and cross-validation of the findings was performed to estimate the accuracy of the algorithm. Results: A total of 227 patients were recruited (101 cases vs. 126 controls). The sensitivity and specificity for the device in our study were 0.91 (95% CI: 0.86–0.93) and 0.91 (95% CI: 0.87–0.94), respectively. In all instances, the observed estimates of PPVs and NPVs were at least 0.82 and 0.90, respectively. The accuracy of the algorithm was not affected by different covariates (including respiratory or valvular conditions). Conclusions: This study demonstrates the efficacy of a contact-free optical device for detecting lung congestion. Further validation of the study results across a larger and precise scale is warranted.

Original languageEnglish
Article number833
JournalBiosensors
Volume12
Issue number10
DOIs
StatePublished - 6 Oct 2022

Bibliographical note

Publisher Copyright:
© 2022 by the authors.

Funding

This research was funded by Donisi Health (formerly ContinUse Biometrics Ltd.), Hanehoshet 6, Tel-Aviv 6971070, Israel.

FundersFunder number
Donisi Health

    Keywords

    • camera
    • congestion
    • contact-free
    • heart failure
    • increased lung fluid content
    • remote monitoring

    Fingerprint

    Dive into the research topics of 'A Contact-Free Optical Device for the Detection of Pulmonary Congestion—A Pilot Study'. Together they form a unique fingerprint.

    Cite this