A brief review of single-cell transcriptomic technologies

Tomer Kalisky, Sarit Oriel, Tali Hana Bar-Lev, Nissim Ben-Haim, Ariel Trink, Yishay Wineberg, Itamar Kanter, Shlomit Gilad, Saumyadipta Pyne

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations

Abstract

In recent years, there has been an effort to develop new technologies formeasuring gene expression and sequence information fromthousands of individual cells. Large data sets that were obtained using these 'single cell' technologies have allowed scientists to address fundamental questions in biomedicine ranging fromstems cells and development to cancer and immunology. Here, we provide a brief review of recent developments in single-cell technology. Our intention is to provide a quick background for newcomers to the field as well as a deeper description of some of the leading technologies to date.

Original languageEnglish
Pages (from-to)64-76
Number of pages13
JournalBriefings in Functional Genomics
Volume17
Issue number1
DOIs
StatePublished - 1 Jan 2018

Bibliographical note

Publisher Copyright:
© The Author 2017.

Keywords

  • Genomics
  • RNA sequencing
  • Single-cell technologies

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