TY - PAT
T1 - 6-phenyl-2-[((piperidin-4-ylmethyl)-piperazin-1YL) or piperazin 1-ylmethyl)-piperidin-1-yl)]-imidazo[2,1-B][1,3,4]thiadiazole derivatives and their use
AU - Nir, U.
AU - Shpungin, Sally
AU - Yaffe, Etai
AU - Cohen, Moshe
N1 - China-patent No. 201080009017.3, EPO-patent No. 10710457.2, USA-patent No. 13/203,172, Israel-patent NO. 214656, France-patent No. 10710457.2, Germany-patent No. 10710457.2, Switzerland- patent No. 10710457.2, UK-patent No. 10710457.2
PY - 2014
Y1 - 2014
N2 - Heterocyclic compounds of formula (I), (II), (III) or a pharmaceutically acceptable salt thereof:
Figure US08653082-20140218-C00001
wherein R1, R2 and R3 are each independently selected from hydrogen, halogen, C1-6alkyl, C2-6alkenyl, N—(C1-6alkyl)2, and N—(C2-6alkenyl)2, the C1-6alkyl and C2-6alkenyl being straight or branched; and Y1 and Y2 are selected from N and CH where one of Y1 and Y2 is N and the other is CH, are provided. Also provided are the synthesis of and pharmaceutical compositions including these compounds. These compounds and pharmaceutical compositions thereof can be used for the treatment of disorders, and in particular, cancer.
AB - Heterocyclic compounds of formula (I), (II), (III) or a pharmaceutically acceptable salt thereof:
Figure US08653082-20140218-C00001
wherein R1, R2 and R3 are each independently selected from hydrogen, halogen, C1-6alkyl, C2-6alkenyl, N—(C1-6alkyl)2, and N—(C2-6alkenyl)2, the C1-6alkyl and C2-6alkenyl being straight or branched; and Y1 and Y2 are selected from N and CH where one of Y1 and Y2 is N and the other is CH, are provided. Also provided are the synthesis of and pharmaceutical compositions including these compounds. These compounds and pharmaceutical compositions thereof can be used for the treatment of disorders, and in particular, cancer.
UR - https://patents.google.com/patent/US8653082B2/en
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M1 - US8653082B2
PB - Urifer Ltd
ER -
