6-Amino-6-deoxy-5,6-di-N-(N′-octyliminomethylidene) nojirimycin: Synthesis, biological evaluation, and crystal structure in complex with acid β-glucosidase

Boris Brumshtein, Matilde Aguilar-Moncayo, Isabel M. García-Moreno, Carmen Ortiz Mellet, José García M. Fernández, Israel Silman, Yoseph Shaaltiel, David Aviezer, Joel L. Sussman, Anthony H. Futerman

Research output: Contribution to journalArticlepeer-review

48 Scopus citations
Original languageEnglish
Pages (from-to)1480-1485
Number of pages6
JournalChemBioChem
Volume10
Issue number9
DOIs
StatePublished - 15 Jun 2009
Externally publishedYes

Keywords

  • Acid beta-glucosidase
  • Gaucher disease
  • Guanidine
  • Iminosugars
  • Inhibitors
  • Nojirimycin

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